Rabbit Anti-TRAPPC6A antibody

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1810073E21Rik; 4930519D19Rik; AI480686; HSPC289; MGC117907; mhyp; OTTMUSP00000025165; OTTMUSP00000025166; rCG_54352; RGD1309160; TPC6A_HUMAN; Trafficking protein particle complex 6A; Trafficking protein particle complex subunit 6A; TRAPP comp

Cat:

SL16587R

Species Reactivity：

(predicted: Human,Dog,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human TRAPPC6A:21-100/159

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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TRAPPC6A is a 159 amino acid protein that localizes to the Golgi apparatus and endoplasmic reticulum. Belonging to the TRAPP small subunits family and the BET3 subfamily, TRAPPC6A may play a role in vesicular transport during the biogenesis of melanosomes. TRAPPC6A is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. TRAPPC6A exists as a heterodimer with TRAPPC3 and undergoes alternative splicing to produce two isoforms. TRAPPC6A is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a variety of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Function:
May play a role in vesicular transport during the biogenesis of melanosomes.

Subunit:
Part of the multisubunit TRAPP (transport protein particle) complex. Heterodimer with TRAPPC3. The heterodimer TRAPPC3-TRAPPC6A interacts with TRAPPC2L. Interacts with TRAPPC2L.

Subcellular Location:
Golgi apparatus; cis-Golgi network. Endoplasmic reticulum.

Similarity:
Belongs to the TRAPP small subunits family. BET3 subfamily.

SWISS:
O75865

Gene ID:
79090

Database links:

Entrez Gene: 79090 Human

Omim: 610396 Human

SwissProt: O75865 Human

Unigene: 466929 Human

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