Rabbit Anti-TRAPPC9 antibody

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1810044A24Rik; 2900005P22Rik; 4632408O18Rik; Ibp; IKBKBBP; Ikk2 binding protein; KIAA1882; MGC4737; MGC4769; mKIAA1882; MRT13; Nibp; NIK and IKK(beta) binding protein; NIK and IKK{beta} binding protein; RGD1309461; T1; Trafficking protein

Cat:

SL16589R

Species Reactivity：

Human,(predicted: Mouse,Rat,Chicken,Dog,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TRAPPC9:101-200/1148

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

Function:
TRAPPC9 functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. It may also function in neuronal cells differentiation and play a role in vesicular transport from endoplasmic reticulum to Golgi.

Subunit:
Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Directly interacts with IKBKB and MAP3K14.

Subcellular Location:
Golgi apparatus; cis-Golgi network. Endoplasmic reticulum. Cytoplasm. Note: Processes and cell bodies of neurons.

Tissue Specificity:
Expressed at high levels in muscle and kidney and to a lower extent in brain, heart and placenta.

DISEASE:
Mental retardation, autosomal recessive 13 (MRT13) [MIM:613192]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the NIBP family.

SWISS:
Q96Q05

Gene ID:
83696

Database links:

Entrez Gene: 83696 Human

Omim: 611966 Human

SwissProt: Q96Q05 Human

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