Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication. Belongs to the influenza viruses PB2 family.
Function:
Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication.
Subunit:
Influenza RNA polymerase is composed of three subunits: PB1, PB2 and PA.
Subcellular Location:
Virion. Host nucleus. Host mitochondrion.
Similarity:
Belongs to the influenza viruses PB2 family.
SWISS:
PO3428
Gene ID:
956536
Database links:
Entrez Gene: 956536 Influenza A
SwissProt: PO3428 Influenza A
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