Rabbit Anti-NOSIP antibody | Sunlong Medical

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CGI 25; CGI-25; NOSIP_HUMAN; CGI25; CGI25 protein; eNOS interacting protein; Nitric oxide synthase interacting protein.

Cat:

SL16652R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human NOSIP:151-250/301

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

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Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]

Function:
NOSIP is a novel type of modulator that promotes translocation of eNOS from the plasma membrane to intracellular sites, thereby uncoupling eNOS from plasma membrane caveolae and inhibiting NO synthesis.

Subunit:
Interacts with NOS1 and NOS3.

Subcellular Location:
Cytoplasm. Nucleus. Note: Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.

Tissue Specificity:
Expressed in heart, brain and lung. Present in endothelial cells (at protein level).

Similarity:
Belongs to the NOSIP family.

SWISS:
Q9Y314

Gene ID:
51070

Database links:

Entrez Gene: 51070 Human

Entrez Gene: 511234 Cow

Entrez Gene: 66394 Mouse

Entrez Gene: 292894 Rat

SwissProt: Q3SWY5 Cow

SwissProt: Q9Y314 Human

SwissProt: Q9D6T0 Mouse

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