Rabbit Anti-INO80B antibody

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2510009I23Rik; hIes2; high mobility group AT hook 1 like 4; High mobility group AT-hook 1-like 4; HMG1YL4; Hmga1l4; IES2; IES2 homolog; IN80B_HUMAN; INO80 complex subunit B; INO80B; PAP (Pim 1 associated protein) associated protein 1; PAP (Pim

Cat:

SL16661R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human INO80B:1-100/356

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript. [provided by RefSeq, Feb 2011]

Function:
Induces growth and cell cycle arrests at the G1 phase of the cell cycle. Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

Subunit:
Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase SLCterminal domain of INO80. Interacts with RP9. {ECO:0000269|PubMed:15556297, ECO:0000269|PubMed:16230350, ECO:0000269|PubMed:18922472, ECO:0000269|PubMed:21303910}.

Subcellular Location:
Nucleus. Nucleus; nucleolus.

Similarity:
Contains 1 HIT-type zinc finger.

SWISS:
Q9C086

Gene ID:
83444

Database links:

Entrez Gene: 83444 Human

Entrez Gene: 70020 Mouse

SwissProt: Q9C086 Human

SwissProt: Q99PT3 Mouse

Unigene: 410786 Human

Unigene: 27814 Mouse

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