This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Function:
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the inositol phosphokinase (IPK) family.
SWISS:
Q9UHH9
Gene ID:
51447
Database links:
Entrez Gene: 51447 Human
Entrez Gene: 416010 Chicken
Entrez Gene: 508236 Cow
Entrez Gene: 76500 Mouse
Entrez Gene: 100009233 Rabbit
Entrez Gene: 59268 Rat
Omim: 606992 Human
SwissProt: Q9UHH9 Human
SwissProt: Q80V72 Mouse
SwissProt: Q95221 Rabbit
SwissProt: Q9R0U1 Rat
Unigene: 595983 Human
Unigene: 276336 Mouse
Unigene: 112574 Rat
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