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Rabbit Anti-TRIM29 (acetyl K116) antibody
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
Function:
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.
Subcellular Location:
Cytoplasm. Colocalizes with intermediate filaments.
Tissue Specificity:
Expressed in placenta, prostate and thymus.
Post-translational modifications:
Constitutively phosphorylated by PKC on serine/threonine in A431 cells.
Similarity:
Contains 1 B box-type zinc finger.
SWISS:
Q14134
Gene ID:
23650
Database links:
Entrez Gene: 23650 Human
Entrez Gene: 525062 Cow
Entrez Gene: 72169 Mouse
Entrez Gene: 300656 Rat
Omim: 610658 Human
SwissProt: Q14134 Human
SwissProt: Q8R2Q0 Mouse
Unigene: 504115 Human
Unigene: 273277 Mouse
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