The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The KK-LSLC1 gene product has been provisionally designated KK-LSLC1 pending further characterization.
Function:
Specifically expressed in testis. Expressed by cancer cell lines.
Subcellular Location:
Cell membrane.
SWISS:
Q5H943
Gene ID:
203413
Database links:
Entrez Gene: 203413 Human
SwissProt: Q5H943 Human
Unigene: 97892 Human
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