This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Subcellular Location:
Cytoplasm > cytoskeleton.
Tissue Specificity:
Expressed in adult fibroblasts and in a range of fetal tissues including tongue, palate, and mandible.
Similarity:
Contains 1 BTB (POZ) domain.
Contains 6 Kelch repeats.
SWISS:
Q9C0H6
Gene ID:
56062
Database links:
Entrez Gene: 56062 Human
Entrez Gene: 237010 Mouse
Omim: 300348 Human
SwissProt: Q9C0H6 Human
Unigene: 49075 Human
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