This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
SWISS:
Q7Z3Z0
Gene ID:
147183
Database links:
Entrez Gene: 147183 Human
SwissProt: Q7Z3Z0 Human
Unigene: 55412 Human
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