The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]
Tissue Specificity:
Early expression in the hair follicle, mainly found in supramatricial cells and lowermost cortical cells of the hair bulb.
Similarity:
Belongs to the intermediate filament family.
SWISS:
Q92764
Gene ID:
3886
Database links:
Entrez Gene: 3886 Human
Omim: 602764 Human
SwissProt: Q92764 Human
Unigene: 73082 Human
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