Rabbit Anti-KAP3.3 antibody

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KRTAP3-3 High sulfur keratin-associated protein 3.3; KAP3.3; Keratin-associated protein 3-3; Keratin-associated protein 3.3; KRA33_HUMAN; Krtap3-3; KRTAP3.3.

Cat:

SL16851R

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human KAP3.3

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]

Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

Tissue Specificity:
Localized to the upper cortex of the hair shaft.

Similarity:
Belongs to the KRTAP type 3 family.

SWISS:
Q9BYR6

Gene ID:
85293

Database links:

Entrez Gene: 713645 Cow

Entrez Gene: 85293 Human

Entrez Gene: 66380 Mouse

Entrez Gene: 363678 Rat

SwissProt: Q24JX9 Cow

SwissProt: Q9BYR6 Human

SwissProt: Q9D7P0 Mouse

Unigene: 662759 Human

Unigene: 30539 Mouse

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