Potassium channels contribute to maintaining cell volume, membrane potential, neuronal excitability and the secretion of transmitters, salt and hormones. Two families of potassium channels have been identified. One family includes the inwardly rectifying potassium channels whereas, the other family includes: voltage sensing (KV); big conductance, calcium activated (BKca); and small conductance, calcium activated (SK) potassium channels. Kv3.2 functions as a delayed rectifier type K+ channel activated by large membrane depolarizations.
Function:
Mediates the voltage-dependent potassium ion
permeability of excitable membranes. Assuming opened or closed
conformations in response to the voltage difference across the
membrane, the protein forms a potassium-selective channel through
which potassium ions may pass in accordance with their
electrochemical gradient. Channel properties are modulated by
subunit assembly (By similarity)
Subunit:
The potassium channel is probably composed of a homo- or
heterotetrameric complex of pore-forming subunits that can
associate with modulating accessory subunits
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the potassium channel family.
SWISS:
Q86W09
Gene ID:
3747
Database links:
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