Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane. [provided by RefSeq, Jul 2013]
Function:
Potassium channel displaying weak inward rectification in symmetrical K(+) solution.
Subcellular Location:
Membrane.
Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
SWISS:
Q9HB14
Gene ID:
56659
Database links:
Entrez Gene: 56659 Human
Entrez Gene: 217826 Mouse
Entrez Gene: 64120 Rat
Omim: 607367 Human
SwissProt: Q9HB14 Human
SwissProt: Q8R1P5 Mouse
SwissProt: Q9ERS0 Rat
Unigene: 510191 Human
Unigene: 312335 Mouse
Unigene: 53793 Rat
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