This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.
Subunit:
Homodimer (Potential).
Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).
Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
SWISS:
Q9Y2U2
Gene ID:
10089
Database links:
Entrez Gene: 10089 Human
Omim: 603940 Human
SwissProt: Q9Y2U2 Human
Unigene: 175218 Human
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