Rabbit Anti-KIAA1191 antibody

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IR2155535; OTTHUMP00000185569; OTTHUMP00000195036; TMEM2L; P33MX_HUMAN; Transmembrane protein 2 like; Putative monooxygenase p33MONOX; Brain-derived rescue factor p60MONOX; Flavin monooxygenase motif-containing protein of 33 kDa.

Cat:

SL16994R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human KIAA1191:51-150/305

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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KIAA1199 belongs to the TMEM2 family and contains 4 PbH1 repeats. It is expressed in the inner ear. It is expressed in cochlea and vestibule tissues and it may be involved in hearing. Defects in KIAA1199 may be a cause of non-syndromic hearing loss. It is also thought that KIAA1199 is a tumor suppressor that may be involved in establishing cellular mortality in normal human cells.

Function:
Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

Subunit:
Interacts with COBRA1, NOL12 and PRNP.

Tissue Specificity:
Down-regulated in the occipital lobe of an early stage Alzheimer disease patients.

Similarity:
Belongs to the P33MONOX family.

SWISS:
Q96A73

Gene ID:
57179

Database links:

Entrez Gene: 57179 Human

SwissProt: Q96A73 Human

Unigene: 519783 Human

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