Rabbit Anti-G2E3 antibody | Sunlong Medical

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KIAA1333 FLJ20333; G2/M phase specific E3 ubiquitin protein ligase; G2E3; PHF7B. G2E3_HUMAN

Cat:

SL17000R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human G2E3:161-250/706

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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KIAA1333 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Essential in early embryonic development to prevent apoptotic death.

Subcellular Location:
Nucleus, nucleolus. Cytoplasm. Note: Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage.

Tissue Specificity:
Predominantly expressed in brain, liver, kidney, testes and ovary.

Similarity:
Contains 1 HECT (E6AP-type E3 ubiquitin-proteinligase) domain.
Contains 3 PHD-type zinc fingers.

SWISS:
Q7L622

Gene ID:
55632

Database links:

Entrez Gene: 55632 Human

Omim: 611299 Human

SwissProt: Q7L622 Human

SwissProt: Q5RJY2 Mouse

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