Home > Product > Antibody > Rabbit Anti-KIAA1688 antibody
ARHGAP39; CrGAP; RHG39_HUMAN; Uncharacterized protein KIAA1688; Vilse.
Cat:
SL17022R
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human KIAA1688:801-900/1083
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. KIAA1688, also known as ARHGAP39 (Rho GTPase activating protein 39), CrGAP or Vilse, is a 1,083 amino acid nuclear protein that contains one MyTH4 domain, one Rho-GAP domain and two WW domains. KIAA1688 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million bases and encodes approximately 800 genes. Chromosome 8 is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.

Function:
KIAA1688 was identified as a hypothetical protein predicted from the in silico analysis of long cDNAS isolated in the Kazusa cDNA sequencing project. The function of KIAA1688 has not been characterized.

Subcellular Location:
Nuclear

Similarity:
Contains 1 MyTH4 domain.
Contains 1 Rho-GAP domain.
Contains 2 WW domains.

SWISS:
Q9C0H5

Gene ID:
80728

Database links:

Entrez Gene: 80728 Human

SwissProt: Q9C0H5 Human

SwissProt: P59281 Mouse



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