Home > Product > Antibody > Rabbit Anti-KIAA1731 antibody
hCG_2036584; K1731_HUMAN; Kiaa1731; Protein KIAA1731.
Cat:
SL17025R
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human KIAA1731:501-600/2601
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


KIAA1737 is a 399 amino acid protein that is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder α1-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies.

Subunit:
May be involved in centriole formation or stability.

Subcellular Location:
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

SWISS:
Q9C0D2

Gene ID:
85459

Database links:

Entrez Gene: 85459 Human

SwissProt: Q9C0D2 Human

Unigene: 458418 Human



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