Rabbit Anti-KIF18A antibody

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AU024633; B130001M12Rik; DKFZp434G2226; KI18A_HUMAN; KIF 18A; KIF18A; kinesin family member 18A; Kinesin like protein KIF18A; Kinesin-like protein KIF18A; Marrow stromal KIF18A; MGC27627; MS KIF18A; MS-KIF18A; RGD1561740; RP23 206C1.1.

Cat:

SL17042R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,Chimpanzee,)

Immunogen：

KLH conjugated synthetic peptide derived from human KIF18A:151-250/398

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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KIF18A is a 898 amino acid protein that contains one kinesin-motor domain, which is responsible for the ATP-dependent movement of KIF18A across microtubules. KIF18A plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. Expression of KIF18A is induced by estrogen.

Function:
Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.

Subcellular Location:
Cell projection > ruffle. Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.

Post-translational modifications:
Glycosylated.
Ubiquitinated.

Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.

SWISS:
Q8NI77

Gene ID:
81930

Database links:

Entrez Gene: 81930 Human

Omim: 611271 Human

SwissProt: Q8NI77 Human

Unigene: 301052 Human

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