Home > Product > Antibody > Rabbit Anti-LAT3 antibody
L type amino acid transporter 3; L-type amino acid transporter 3; Large neutral amino acids transporter small subunit 3; LAT3_HUMAN; PB39; POV1; Prostate cancer overexpressed gene 1 protein; R00504; SLC43A1; Solute carrier family 43 member 1.
Cat:
SL17110R
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human LAT3:101-200/559
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
More
Unit:
Price: $
Product PDFs
Datasheet:


SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]

Function:
Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.

Subcellular Location:
Membrane.

Tissue Specificity:
In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.

Similarity:
Belongs to the SLC43A transporter (TC 2.A.1.44) family.

SWISS:
O75387

Gene ID:
8501

Database links:

Entrez Gene: 8501 Human

Omim: 603733 Human

SwissProt: O75387 Human

Unigene: 591952 Human

Unigene: 735724 Human



Product Feedback Wall
Message :
Your Email :
Copyright © 2007-2018 Sunlong Medical All Rights Reserved.