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Home > Product > Antibody > Rabbit Anti-SOX5 antibody
L SOX5; MGC35153; Sex determining region Y box 5; SOX 5; SOX-5; SOX 5 protein; Sox5; SOX5 protein; SOX5_HUMAN; SRY (sex determining region Y) box 5; SRY box 5; Transcription factor SOX 5; Transcription factor SOX-5; Transcription factor SOX5
Cat:
SL17136R
Species Reactivity：
(predicted: Human,Mouse,Rat,)
Immunogen：
KLH conjugated synthetic peptide derived from human SOX5:121-220/763
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Function:
Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 HMG box DNA-binding domain.

SWISS:
P35711

Gene ID:
6660

Database links:

Entrez Gene: 6660 Human

Entrez Gene: 20678 Mouse

Entrez Gene: 140587 Rat

Omim: 604975 Human

SwissProt: P35711 Human

SwissProt: P35710 Mouse

Unigene: 657542 Human

Unigene: 1752 Mouse

Unigene: 482428 Mouse



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