Home > Product > Antibody > Rabbit Anti-TRMT5 antibody
KIAA1393; M1G methyltransferase; M1G-methyltransferase; TRM5; TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae); TRMT5; TRMT5_HUMAN; tRNA (guanine-N(1)-)-methyltransferase; tRNA [GM37] methyltransferase; tRNA methyltransferase 5; tRNA N1G37
Cat:
SL17145R
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human TRMT5:201-300/509
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008]

Function:
Specifically methylates guanosine-37 in various tRNAs. Not dependent on the nature of the nucleoside 5' of the target nucleoside.

Subunit:
Monomer.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the TRM5 / TYW2 family.

SWISS:
Q32P41

Gene ID:
57570

Database links:

Entrez Gene: 57570 Human

Entrez Gene: 76357 Mouse

Omim: 611023 Human

SwissProt: Q32P41 Human

SwissProt: Q9D0C4 Mouse

Unigene: 380159 Human

Unigene: 311344 Mouse



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