Rabbit Anti-TRNT1 antibody | Sunlong Medical

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AA408384; C76540; CCA adding; CCA1; CGI 47; EC 2.7.7.25; Mitochondrial CCA adding tRNA nucleotidyltransferase; Mitochondrial tRNA nucleotidyl transferase, CCA adding; mt CCA adding enzyme; mt Trat; mt tRNA adenylyltransferase; mt tRNA CCA dipho

Cat:

SL17149R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TRNT1:351-434/434

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. This reaction is a fundamental prerequisite for mature tRNAs to become aminoacylated and to participate in protein biosynthesis (Lizano et al., 2007 [PubMed 17204286]).[supplied by OMIM, Aug 2009]

Function:
TRNT1 belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. It adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates.

Subunit:
Monomer, and homodimer; disulfide-linked.

Subcellular Location:
Mitochondrial

Similarity:
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

SWISS:
Q96Q11

Gene ID:
51095

Database links:

Entrez Gene: 51095 Human

Entrez Gene: 70047 Mouse

Entrez Gene: 312616 Rat

Entrez Gene: 415249 Zebrafish

Omim: 612907 Human

SwissProt: Q96Q11 Human

SwissProt: Q8K1J6 Mouse

SwissProt: Q4VSH2 Rat

SwissProt: Q6IQR7 Zebrafish

Unigene: 567495 Human

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