Rabbit Anti-SCAND2 antibody

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SCAN domain containing 2; SCAN domain containing protein 2; SCAND 2.

Cat:

SL17267R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human SCAND2:1-100/306

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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SCAND2 is a 306 amino acid nuclear protein that may play a role in the mechanism of transcriptional regulation. SCAND2 contains one SCAN box domain and, unlike most SCAN box domain-containing proteins, is devoid of a C2H2-type zinc-finger domain. The SCAN box domain is a conserved leucine rich motif, approximately 60 amino acids in length, that participates in protein-protein interactions. The SCAND2 gene is a fusion gene created by the retropositioning of a PHD2 (also known as EGLN1) gene copy from chromosome 1 onto an ancestral SCAN zinc finger gene, followed by exon shuffling. The resulting SCAND2 gene product has an N-terminal SCAN domain and a SLCterminus derived from the PHD2 gene. SCAND2 exists as 2 isoforms produced by alternative splicing.

Function:
SCAND2 contains a SCAN domain, an 80 amino acid residue sequence with a L-X(6)-L motif at its core. This core is flanked by A, E, L, M, H and C residues that are frequently found in alpha-helices. The function of SCAND2 has not been determined.

Subcellular Location:
Nuclear

SWISS:
Q9GZW5

Gene ID:
54581

Database links:

Entrez Gene: 54581 Human

Omim: 610417 Human

SwissProt: Q9GZW5 Human

Unigene: 658114 Human

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