This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Function:
Seems to protects cells by scavenging oxidative molecules or harmful products of oxidation.
Subcellular Location:
Endoplasmic reticulum membrane. Golgi apparatus membrane. Endoplasmic reticulum and/or Golgi.
Tissue Specificity:
Expressed ubiquitously.
Similarity:
Contains 2 collagen-like domains.
SWISS:
Q6AZY7
Gene ID:
51435
Database links:
Entrez Gene: 51435 Human
Entrez Gene: 219151 Mouse
Entrez Gene: 36885 Rat
Omim: 602728 Human
SwissProt: Q6AZY7 Human
SwissProt: Q8C850 Mouse
SwissProt: D3ZPA7 Rat
Unigene: 128856 Human
Unigene: 38895 Mouse
|
|