Rabbit Anti-LAP1B antibody | Sunlong Medical

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Lamin-associated protein 1B; Lamina associated polypeptide 1B; Lamina associated polypeptide 1C; LAP1; LAP1B; TOIP1_HUMAN; TOR1AIP1; Torsin A interacting protein 1; Torsin-1A-interacting protein 1.

Cat:

SL17325R

Species Reactivity：

(predicted: Human,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human LAP1B:51-150/583

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a type 2 integral membrane protein that binds A- and B-type laminins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Function:
Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.

Subcellular Location:
Nucleus inner membrane.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the TOR1AIP family.

SWISS:
Q5JTV8

Gene ID:
26092

Database links:

Entrez Gene: 26092 Human

SwissProt: Q5JTV8 Human

Unigene: 496459 Human

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