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Rabbit Anti-HS6ST2 antibody
Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. This gene encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
Subcellular Location:
Membrane.
Similarity:
Belongs to the sulfotransferase 6 family.
SWISS:
Q96MM7
Gene ID:
90161
Database links:
Entrez Gene: 90161 Human
Omim: 300545 Human
SwissProt: Q96MM7 Human
Unigene: 385956 Human
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