Rabbit Anti-HISPPD2A/IP6 Kinase antibody

Home > Product > Antibody > Rabbit Anti-HISPPD2A/IP6 Kinase antibody

Histidine acid phosphatase domain-containing protein 2A; hsVIP1; Inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinase 1; Inositol pyrophosphate synthase 1; InsP6 and PP IP5 kinase 1; IP6 kinase; IP6K; IPS1; PP IP5 kinase 1; PP

Cat:

SL17407R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human HISPPD2A:661-760/1433

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.[provided by RefSeq, Jun 2010]

Function:
Bifunctional inositol kinase that catalyzes the formation of diphosphoinositol pentakisphosphate (InsP7 or PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (InsP8 or PP2-InsP4). Converts inositolitol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Probably specifically mediates the formation of 4PP-InsP5 and 6PP-InsP5 InsP7 isomers but not of 5PP-IP5 InsP7 isomer. Activated when cells are exposed to hyperosmotic stress.

Subcellular Location:
Cytoplasm, cytosol.

Tissue Specificity:
Widely expressed, with a higher expression in skeletal muscle, heart and brain.

Similarity:
Belongs to the histidine acid phosphatase family. VIP1 subfamily.

SWISS:
Q6PFW1

Gene ID:
9677

Database links:

Entrez Gene: 9677 Human

Omim: 610979 Human

SwissProt: Q6PFW1 Human

Product Feedback Wall