Rabbit Anti-Histatin 1 antibody

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HIS1; Histidine rich protein 1; HTN1; Post PB protein; PPB.

Cat:

SL17412R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human Histatin 1:21-57/57

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Histatin 1 is a histidine-rich phosphoprotein present in human parotid saliva that possesses candidacidal activity and functions in mineralization by adsorbing to hydroxyapatite. Phosphorylation of histatin 1 contributes to its ability to bind hydroxyapatite. Salivary histatins are a family of small histidine-rich peptides with potent antifungal activity. Submandibular and sublingual histatin secretion levels may affect the status of yeast present in the mouth. As a result, histatins have been implicated as potential therapeutic agents against oral candidiasis. A decrease in salivary histatins in relation to total salivary protein is common in old age and can influence the ability of the oral host defense system to address pathogens.

Function:
Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities.

Subcellular Location:
Secreted

SWISS:
P15515

Gene ID:
3346

Database links:

Entrez Gene: 3346 Human

Omim: 142701 Human

SwissProt: P15515 Human

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