Home > Product > Antibody > Rabbit Anti-HIVEP1 antibody
Cirhin interaction protein; CIRIP; CRYBP1; GAAP; Gate keeper of apoptosis-activating protein; HIV EP1; HIV-EP1; HIVEP 1; Hivep1; Human immunodeficiency virus type I enhancer binding protein 1; Human immunodeficiency virus type I enhancer-binding
Cat:
SL17459R
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human HIVEP1:2001-2100/2718
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


This protein specifically binds to the DNA sequence 5'-GGGACTTTCSLC3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HISLV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HISLV1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HISLV1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.

Subcellular Location:
Cytoplasm. Nucleus and Nucleus.

Similarity:
Contains 5 C2H2-type zinc fingers.

SWISS:
P15822

Gene ID:
3096

Database links:

Entrez Gene: 3096 Human

Omim: 194540 Human

SwissProt: P15822 Human

Unigene: 567284 Human



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