Home
>
Product
>
Antibody
>
Rabbit Anti-HIVEP1 antibody
This protein specifically binds to the DNA sequence 5'-GGGACTTTCSLC3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HISLV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HISLV1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HISLV1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.
Subcellular Location:
Cytoplasm. Nucleus and Nucleus.
Similarity:
Contains 5 C2H2-type zinc fingers.
SWISS:
P15822
Gene ID:
3096
Database links:
Entrez Gene: 3096 Human
Omim: 194540 Human
SwissProt: P15822 Human
Unigene: 567284 Human
|
|