Rabbit Anti-CD172b antibody

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CD172 antigen like family member B; CD172b; CD172b antigen; DKFZp686A05192; Signal regulatory protein beta 1; SIRP BETA 1; SIRP beta 1 isoform 3.

Cat:

SL17500R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human CD172b:51-150/398<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by the SIRPß1 gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins which are known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPß1 was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Subcellular Location:
Cell Membrane; single-pass type I membrane protein

SWISS:
O00241

Gene ID:
10326

Database links:

Entrez Gene: 10326 Human

Omim: 603889 Human

SwissProt: O00241 Human

SwissProt: Q5TFQ8 Human

Unigene: 664861 Human

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