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Rabbit Anti-Pepsin A antibody
Pepsin is a digestive enzyme with particularly broad specificity. It is stored as pepsinogen, so only released when needed. In the stomach, chief cells release pepsinogen. The hormone gastrin and the vagus nerve trigger the release of both pepsinogen and HCl from the stomach lining when food is ingested. HCl creates an acidic environment which allows pepsinogen to unfold and cleave itself in an autocatalytic fashion, thereby generating pepsin (the active form). Pepsin may then cleave the dietary proteins into smaller peptides.
Subcellular Location:
Secreted.
SWISS:
P00791
Gene ID:
396892
Database links:
Entrez Gene: 396892 Pig
SwissProt: P00791 Pig
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