The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008]
Function:
Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.
Subcellular Location:
Belongs to the protein kinase superfamily.
STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 protein kinase domain.
Tissue Specificity:
Ubiquitously expressed in all tissue examined.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
SWISS:
O95747
Gene ID:
9943
Database links:
Entrez Gene: 9943 Human
Entrez Gene: 108737 Mouse
Omim: 604046 Human
SwissProt: O95747 Human
SwissProt: Q6P9R2 Mouse
Unigene: 475970 Human
Unigene: 293565 Mouse
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