Rabbit Anti-Oxytocin antibody

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MGC126890; MGC126892; NEU1_HUMAN; Neurophysin 1; Neurophysin 1 Precursor; Neurophysin I; Ocytocin; OT; OT NPI; OXT; Oxy; Oxytocin neurophysin 1 precursor; Oxytocin Neurophysin preproprotein; Oxytocin prepro (neurophysin I); Oxytocin prepropep

Cat:

SL17581R

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,Sheep,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human Oxytocin:20-28/125

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]

Function:
Neurophysin 1 specifically binds oxytocin.
Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.

Subcellular Location:
Secreted

Similarity:
Belongs to the vasopressin/oxytocin family.

SWISS:
P01178

Gene ID:
5020

Database links:

Entrez Gene: 5020 Human

Entrez Gene: 18429 Mouse

Entrez Gene: 25504 Rat

Omim: 167050 Human

SwissProt: P01178 Human

SwissProt: P35454 Mouse

SwissProt: P01177 Pig

SwissProt: P13389 Sheep

Unigene: 113216 Human

Unigene: 48915 Rat

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