Rabbit Anti-SPANXD/CT11.4 antibody

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Cancer/testis antigen 11.4; Cancer/testis antigen family 11 member 4; CT11.4; dJ171K16.1; Nuclear associated protein SPAN Xd; Nuclear-associated protein SPAN-Xd; SPAN Xd protein; SPANX C; SPANX D; SPANX family member D; SPANX-D; SPANXD; Sperm

Cat:

SL17621R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human SPANXD/CT11.4:21-80/97

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014]

Subcellular Location:
Cytoplasm. Nucleus. Associated with nuclear craters.

Tissue Specificity:
Detected in testis, sperm and a melanoma cell line.

Similarity:
Belongs to the SPAN-X family.

SWISS:
Q9BXN6

Gene ID:
64648

Database links:

Entrez Gene: 64648 Human

Omim: 300670 Human

SwissProt: Q9BXN6 Human

Unigene: 375036 Human

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