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Rabbit Anti-SPATA2L antibody
The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The gene encoding SPATS2L maps to human locus 2q33.1.
Similarity:
Belongs to the SPATA2 family.
SWISS:
Q8IUW3
Gene ID:
14844
Database links:
Entrez Gene: 14844 Human
Entrez Gene: 498963 Rat
SwissProt: Q8IUW3 Human
Unigene: 374556 Human
Unigene: 91547 Rat
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