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Rabbit Anti-SPATA6 antibody
SPATA6 is a 488 amino acid secreted protein that may be involved in spermatid maturation or sperm function. SPATA6 is expressed during embryonic development and is localized in neural tube, somites and limb buds of mouse embryo. Existing as two isoforms produced by alternative splicing events, the gene encoding SPATA6 maps to mouse chromosome 4 and human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Function:
SPATA6 belongs to the SPATA6 family. SPATA6 may play a role in spermatid maturation or sperm function.
Subcellular Location:
Secreted
Similarity:
Belongs to the SPATA6 family.
SWISS:
Q9NWH7
Gene ID:
54558
Database links:
Entrez Gene: 54558 Human
Entrez Gene: 67946 Mouse
Entrez Gene: 171413 Rat
Omim: 613947 Human
SwissProt: Q9NWH7 Human
SwissProt: Q3U6K5 Mouse
SwissProt: Q99MU5 Rat
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