Rabbit Anti-Speedy protein C antibody

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hSpy/Ringo C; Rapid inducer of G2/M progression in oocytes C; Rapid inducer of G2/M progression in oocytes, Xenopus, homolog of, C; RINGO C; Ringo2; SPDYC; SPDYC_HUMAN; speedy C; speedy homolog C; Speedy protein C; Speedy, Xenopus, homolog of, C

Cat:

SL17660R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human Speedy protein C:201-293/293

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

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Other Information
Citations
Protein Attributes
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Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2.

Function:
Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correctlocalization of the active form of Aurora B in prometaphase.

Subunit:
Interacts with CDK1 and CDK2. Interacts with AURKB.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis.

DISEASE:
Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis.

Similarity:
Belongs to the Speedy/Ringo family.

SWISS:
Q5MJ68

Gene ID:
387778

Database links:

Entrez Gene: 387778 Human

Omim: 614030 Human

SwissProt: Q5MJ68 Human

Unigene: 450642 Human

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