Rabbit Anti-SPEM1 antibody | Sunlong Medical

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C17orf83; Spem1; SPEM1_HUMAN; Spermatid maturation 1; Spermatid maturation protein 1.

Cat:

SL17652R

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human SPEM1:201-300/309

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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SPEM1 is a 309 amino acid transmembrane and cytoplasmic protein that is required for proper cytoplasm removal during spermatogenesis. SPEM1 interacts with both Ran BP-17 and PLISLC1. Since PLISLC1 functions through binding and directing poly-ubiquitinated proteins to the proteasome for degradation, interactions between PLISLC1 and SPEM1 suggest a role in the regulation of protein ubiquitination during spermiogenesis. The SPEM1 gene maps to human chromosome 17p13.1. Comprising over 2.5% of the human genome, chromosome 17 consists of about 81 million bases, encodes over 1,200 genes and has the highest gene density in the genome. Chromosome 17 is also enriched in segmental duplications, ranking third in density among the autosomes.

Function:
Required for proper cytoplasm removal during spermatogenesis.

Subcellular Location:
Membrane. Cytoplasm.

SWISS:
Q8N4L4

Gene ID:
374768

Database links:

Entrez Gene: 374768 Human

SwissProt: Q8N4L4 Human

Unigene: 710599 Human

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