Rabbit Anti-SPHKAP antibody

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A-kinase anchor protein SPHKAP; DKFZp781H143; DKFZp781J171; KIAA1678; MGC132614; MGC132616; SKIP; Sphingosine kinase type 1-interacting protein; SPHK1 (sphingosine kinase type 1) interacting protein; SPHK1 interactor, AKAP domain containing; ; S

Cat:

SL17662R

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SPHKAP:1131-1230/1700

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.

Subunit:
Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.

Subcellular Location:
Cytoplasm. Colocalizes with SPHK1 in the cytoplasm.

Tissue Specificity:
Highly expressed in heart. Both isoforms abundantly expressed in ventricle. Also expressed in spleen, ovary and brain.

Similarity:
Belongs to the AKAP110 family.

SWISS:
Q2M3C7

Gene ID:
80309

Database links:

Entrez Gene: 80309 Human

Entrez Gene: 77629 Mouse

Omim: 611646 Human

SwissProt: Q2M3C7 Human

SwissProt: Q6NSW3 Mouse

Unigene: 436306 Human

Unigene: 154303 Mouse

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