The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found. [provided by RefSeq, Jul 2008]
Subcellular Location:
Mitochondrion matrix.
Similarity:
Belongs to the citrate synthase family.
SWISS:
O75390
Gene ID:
1431
Database links:
Entrez Gene: 280682 Cow
Entrez Gene: 1431 Human
Entrez Gene: 12974 Mouse
Entrez Gene: 397519 Pig
Entrez Gene: 170587 Rat
Entrez Gene: 322339 Zebrafish
Omim: 118950 Human
SwissProt: Q29RK1 Cow
SwissProt: O75390 Human
SwissProt: Q9CZU6 Mouse
SwissProt: P00889 Pig
SwissProt: Q8VHF5 Rat
SwissProt: Q7ZVY5 Zebrafish
Unigene: 430606 Human
Unigene: 728168 Human
Unigene: 58836 Mouse
Unigene: 66581 Rat
Unigene: 2432 Zebrafish
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