In human, the four current members of the microrchidia (morc) gene family share an N-terminal ATPase-like ATP-binding region and a CW four-cysteine zinc-finger motif. The protein encoded by this gene also has a nuclear matrix binding domain and a two-stranded coiled-coil motif near its SLCterminus. This gene is widely expressed at low levels in normal tissues and has elevated expression in placenta and testis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]
Subcellular Location:
Nucleus
Tissue Specificity:
Expressed at low levels in normal tissues, with highest expression levels in placenta and testis. Expression is significantly increased in subset of diffuse large B-cell lymphomas.
Similarity:
Contains 1 CW-type zinc finger.
SWISS:
Q8TE76
Gene ID:
79710
Database links:
Entrez Gene: 79710 Human
Entrez Gene: 75746 Mouse
Entrez Gene: 315914 Rat
SwissProt: Q8TE76 Human
SwissProt: Q8BMD7 Mouse
Unigene: 496544 Human
Unigene: 15934 Rat
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