This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Function:
Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 homeobox DNA-binding domain.
SWISS:
P50221
Gene ID:
4222
Database links:
Entrez Gene: 4222 Human
Entrez Gene: 17285 Mouse
Entrez Gene: 363684 Rat
Omim: 600147 Human
SwissProt: P50221 Human
SwissProt: P32442 Mouse
Unigene: 438 Human
Unigene: 3404 Mouse
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