Rabbit Anti-MPHOSPH10 antibody

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M phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); M phase phosphoprotein 10; MPHOSPH 10; Mphosph10; MPP 10; MPP 10P; MPP10; MPP10_HUMAN; MPP10P; U3 small nucleolar ribonucleoprotein protein mpp10.

Cat:

SL17735R

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human MPHOSPH10:331-430/681

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:1000-5000IHC-P=1:50-200IHC-F=1:50-200ICC=1:50-200IF=1:50-200（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing. [provided by RefSeq, Dec 2010]

Function:
Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.

Subcellular Location:
Nucleus > nucleolus. Chromosome. Fibrillar region of the nucleolus. After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase. In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin. The reassociation with nucleolus is preceeded by the arrival of fibrillarin.

Post-translational modifications:
Phosphorylated in M (mitotic) phase.

Similarity:
Belongs to the MPP10 family.

SWISS:
O00566

Gene ID:
10199

Database links:

Entrez Gene: 10199 Human

Entrez Gene: 67973 Mouse

Entrez Gene: 293828 Rat

Omim: 605503 Human

SwissProt: O00566 Human

SwissProt: Q810V0 Mouse

Unigene: 656208 Human

Unigene: 26973 Mouse

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