Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the ribosomal protein L1P family.
SWISS:
Q9BYD6
Gene ID:
65008
Database links:
Entrez Gene: 65008 Human
Entrez Gene: 289491 Rat
Omim: 611821 Human
SwissProt: Q9BYD6 Human
Unigene: 56419 Human
Unigene: 93038 Rat
|
|