Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008]
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the ribosomal protein L15P family.
SWISS:
Q9P015
Gene ID:
29088
Database links:
Entrez Gene: 29088 Human
Entrez Gene: 27395 Mouse
Entrez Gene: 297799 Rat
Entrez Gene: 445041 Zebrafish
Omim: 611828 Human
SwissProt: Q9P015 Human
SwissProt: Q9CPR5 Mouse
SwissProt: Q6DGM3 Zebrafish
Unigene: 18349 Human
Unigene: 182927 Mouse
Unigene: 77890 Zebrafish
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