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Rabbit Anti-MRPL24 antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Function:
MRPL24 is a mitochondrial ribosomal protein (MRP). Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. This is a 39S subunit protein.
Subcellular Location:
Mitochondrial
Similarity:
Belongs to the ribosomal protein L24P family;
Contains 1 KOW domain.
SWISS:
Q96A35
Gene ID:
75590
Database links:
Entrez Gene: 79590 Human
Entrez Gene: 67707 Mouse
Entrez Gene: 295224 Rat
Omim: 611836 Human
SwissProt: Q96A35 Human
SwissProt: Q9CQ06 Mouse
SwissProt: Q66H47 Rat
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