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Rabbit Anti-MRPL36 antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p. [provided by RefSeq, Jul 2008]
Function:
Component of the large subunit of the mitochondrial ribosome.
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the ribosomal protein L36P family.
SWISS:
Q9P0J6
Gene ID:
64979
Database links:
Entrez Gene: 64979
Human
Entrez Gene: 94066 Mouse
Omim: 611842 Human
SwissProt: Q9P0J6 Human
SwissProt: Q99N90 Mouse
Unigene: 719465 Human
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