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Rabbit Anti-MRPL44 antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
Function:
MRPL44 is a component of the 39S subunit of mitochondrial ribosome.
Subcellular Location:
Mitochondrial
Similarity:
Contains 1 DRBM (double-stranded RNA-binding) domain.
Contains 1 RNase III domain.
SWISS:
Q9H9J2
Gene ID:
65080
Database links:
Entrez Gene: 65080 Human
Entrez Gene: 69163 Mouse
Entrez Gene: 301552 Rat
Omim: 611849 Human
SwissProt: Q9H9J2 Human
SwissProt: Q9CY73 Mouse
Unigene: 203559 Human
Unigene: 238455 Mouse
Unigene: 3298 Rat
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